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Avascular necrosis of the head of femur(ANFH)

MedGen UID:
140823
•Concept ID:
C0410480
•
Pathologic Function
Synonyms: FEMORAL HEAD, ASEPTIC NECROSIS OF; FEMORAL HEAD, AVASCULAR NECROSIS OF; ISCHEMIC NECROSIS OF FEMORAL HEAD; OSTEONECROSIS OF FEMORAL HEAD
SNOMED CT: Avascular necrosis of head of femur (203476003); Aseptic necrosis of head of femur (203476003); Osteonecrosis of head of femur (203476003)
 
Related genes: TRPV4, COL2A1
 
OMIM®: 608805

Definition

Necrotic changes in the bone tissue of the femoral head due to interruption of blood supply. [from NCI]

Professional guidelines

PubMed

Shock wave treatment in medicine.
Shrivastava SK, Kailash
J Biosci 2005 Mar;30(2):269-75. doi: 10.1007/BF02703708. PMID: 15933416

Recent clinical studies

Etiology

Pulmonary Hypertension and Left Ventricular Geometric Types in Sickle Cell Anemia.
Oni OO, Odeyemi AO, Olasinde YT, Odeyemi AO, Olufemi-Aworinde KJ, Abolarin AT, Ala OA
Am J Cardiol 2023 Sep 15;203:175-183. Epub 2023 Jul 25 doi: 10.1016/j.amjcard.2023.06.100. PMID: 37499597
Total hip replacement in sickle cell disorder: A preliminary report of challenges and early outcome of 21 consecutive patients.
Katchy AU, Anyaehie UE, Nwadinigwe CU, Eyichukwu GO
Niger J Clin Pract 2018 Apr;21(4):492-495. doi: 10.4103/njcp.njcp_182_17. PMID: 29607863
Serum-cobalt levels with metal-on-metal bearings in the cement-free total hip arthroplasty results covering two years; prospective study.
Weissinger M, Grübl A, Pöll G
Acta Chir Orthop Traumatol Cech 2011;78(5):410-5. PMID: 22094154

Diagnosis

Invasive pneumococcal disease serotype 23B1 causing multifocal septic arthritis, myositis and retroperitoneal abscess.
Drummond K, Holmes NE
BMJ Case Rep 2024 Jan 16;17(1) doi: 10.1136/bcr-2023-257318. PMID: 38233006Free PMC Article
Losing your head? An evaluation of the readability and reliability of patient information available online for avascular necrosis of the head of the femur.
Downes A, Stanley C, Donnelly R, Murphy T
Surgeon 2023 Dec;21(6):e323-e327. Epub 2023 May 26 doi: 10.1016/j.surge.2023.05.002. PMID: 37244775
Value of SPECT/CT in the diagnosis of avascular necrosis of the head of femur: A meta-analysis.
Iqbal B, Currie G
Radiography (Lond) 2022 May;28(2):560-564. Epub 2021 Dec 16 doi: 10.1016/j.radi.2021.11.012. PMID: 34922825

Therapy

Survival of total hip arthroplasty (THA) in sickle cell disease.
AlOmran AS
Arch Orthop Trauma Surg 2023 Dec;143(12):7213-7218. Epub 2023 Jul 19 doi: 10.1007/s00402-023-04986-9. PMID: 37466724
Osteotomies for avascular necrosis of the femoral head.
Quaranta M, Miranda L, Oliva F, Aletto C, Maffulli N
Br Med Bull 2021 Mar 25;137(1):98-111. doi: 10.1093/bmb/ldaa044. PMID: 33454780
Total hip replacement in sickle cell disorder: A preliminary report of challenges and early outcome of 21 consecutive patients.
Katchy AU, Anyaehie UE, Nwadinigwe CU, Eyichukwu GO
Niger J Clin Pract 2018 Apr;21(4):492-495. doi: 10.4103/njcp.njcp_182_17. PMID: 29607863
Shock wave treatment in medicine.
Shrivastava SK, Kailash
J Biosci 2005 Mar;30(2):269-75. doi: 10.1007/BF02703708. PMID: 15933416
Avascular necrosis of the head of femur after intramedullary nailing for fracture of the shaft of the femur.
Shahane SA, Farhan MJ
Injury 1996 Nov;27(9):663-5. doi: 10.1016/s0020-1383(96)00109-x. PMID: 9039366

Prognosis

Pulmonary Hypertension and Left Ventricular Geometric Types in Sickle Cell Anemia.
Oni OO, Odeyemi AO, Olasinde YT, Odeyemi AO, Olufemi-Aworinde KJ, Abolarin AT, Ala OA
Am J Cardiol 2023 Sep 15;203:175-183. Epub 2023 Jul 25 doi: 10.1016/j.amjcard.2023.06.100. PMID: 37499597
Total hip replacement in sickle cell disorder: A preliminary report of challenges and early outcome of 21 consecutive patients.
Katchy AU, Anyaehie UE, Nwadinigwe CU, Eyichukwu GO
Niger J Clin Pract 2018 Apr;21(4):492-495. doi: 10.4103/njcp.njcp_182_17. PMID: 29607863
Traumatic anterior hip dislocation in a 12-year-old child.
Gupta V, Kaur M, Kundu ZS, Kaplia A, Singh D
Chin J Traumatol 2013;16(2):122-5. PMID: 23540904
Traumatic dislocation of the hip.
Reigstad A
J Trauma 1980 Jul;20(7):603-6. doi: 10.1097/00005373-198007000-00010. PMID: 7392111
Fracture of the neck of femur in childhood.
Rea E
Med J Zambia 1980 Aug-Sep;14(5):89-90. PMID: 7053010

Clinical prediction guides

Survival of total hip arthroplasty (THA) in sickle cell disease.
AlOmran AS
Arch Orthop Trauma Surg 2023 Dec;143(12):7213-7218. Epub 2023 Jul 19 doi: 10.1007/s00402-023-04986-9. PMID: 37466724
Losing your head? An evaluation of the readability and reliability of patient information available online for avascular necrosis of the head of the femur.
Downes A, Stanley C, Donnelly R, Murphy T
Surgeon 2023 Dec;21(6):e323-e327. Epub 2023 May 26 doi: 10.1016/j.surge.2023.05.002. PMID: 37244775
Osteotomies for avascular necrosis of the femoral head.
Quaranta M, Miranda L, Oliva F, Aletto C, Maffulli N
Br Med Bull 2021 Mar 25;137(1):98-111. doi: 10.1093/bmb/ldaa044. PMID: 33454780
Total hip replacement in sickle cell disorder: A preliminary report of challenges and early outcome of 21 consecutive patients.
Katchy AU, Anyaehie UE, Nwadinigwe CU, Eyichukwu GO
Niger J Clin Pract 2018 Apr;21(4):492-495. doi: 10.4103/njcp.njcp_182_17. PMID: 29607863
Fracture of the neck of femur in childhood.
Rea E
Med J Zambia 1980 Aug-Sep;14(5):89-90. PMID: 7053010

Recent systematic reviews

Osteotomies for avascular necrosis of the femoral head.
Quaranta M, Miranda L, Oliva F, Aletto C, Maffulli N
Br Med Bull 2021 Mar 25;137(1):98-111. doi: 10.1093/bmb/ldaa044. PMID: 33454780

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